| Italy Serie A 2021-22 Standings ʕ\ | |||||||||||||||
| Pos. | Club | Pt. | W | D | L | goals | Dif. | M. | Notes | ||||||
| 1 | AC Milan | 86 | 26 | 8 | 4 | 69:31 | 38 | 38 | Champions League | ||||||
| 2 | Inter Milan | 84 | 25 | 9 | 4 | 84:32 | 52 | 38 | Champions League | ||||||
| 3 | SSC Napoli | 79 | 24 | 7 | 7 | 74:31 | 43 | 38 | Champions League | ||||||
| 4 | Juventus FC | 70 | 20 | 10 | 8 | 57:37 | 20 | 38 | Champions League | ||||||
| 5 | Lazio Roma | 64 | 18 | 10 | 10 | 77:58 | 19 | 38 | Europa League | ||||||
| 6 | AS Roma | 63 | 18 | 9 | 11 | 59:43 | 16 | 38 | Europa League | ||||||
| 7 | ACF Fiorentina | 62 | 19 | 5 | 14 | 59:51 | 8 | 38 | Europa League Quali. | ||||||
| 8 | Atalanta BC | 59 | 16 | 11 | 11 | 65:48 | 17 | 38 | |||||||
| 9 | Hellas Verona | 53 | 14 | 11 | 13 | 65:59 | 6 | 38 | |||||||
| 10 | Torino FC | 50 | 13 | 11 | 14 | 46:41 | 5 | 38 | |||||||
| 11 | Sassuolo Calcio | 50 | 13 | 11 | 14 | 64:66 | -2 | 38 | |||||||
| 12 | Udinese Calcio | 47 | 11 | 14 | 13 | 61:58 | 3 | 38 | |||||||
| 13 | Bologna FC | 46 | 12 | 10 | 16 | 44:55 | -11 | 38 | |||||||
| 14 | Empoli FC | 41 | 10 | 11 | 17 | 50:70 | -20 | 38 | |||||||
| 15 | Sampdoria | 36 | 10 | 6 | 22 | 46:63 | -17 | 38 | |||||||
| 16 | Spezia Calcio | 36 | 10 | 6 | 22 | 41:71 | -30 | 38 | |||||||
| 17 | US Salernitana 1919 | 31 | 7 | 10 | 21 | 33:78 | -45 | 38 | |||||||
| 18 | Cagliari Calcio | 30 | 6 | 12 | 20 | 34:68 | -34 | 38 | Relegation | ||||||
| 19 | Genoa CFC | 28 | 4 | 16 | 18 | 27:60 | -33 | 38 | Relegation | ||||||
| 20 | Venezia FC | 27 | 6 | 9 | 23 | 34:69 | -35 | 38 | Relegation | ||||||